Research

Researchers at the Department of Ophthalmology, Boston Children’s Hospital, and the Harvard Medical School, have reported that the interface of photoreceptors and RPE in Stargardt… Read More »Analysis of data from AO-SLO images on Stargardt disease patients show clear profiles of hyper-reflective bands, potentially targeted for pharmaceutical treatment.

In a recent study published in the prestigious journal Nature Communications (2024 Jul 21;15[1]:6150), researchers have reported that an upstream regulator, “AKT2” (a member of… Read More »Researchers identify that lysosomal biogenesis and mitochondrial signalling may suggest new therapeutic targets for dry-AMD.

Researchers at the School of Pharmacy, University of Eastern Finland, and the Gavin Herbert Eye Institute-Center for Translational Vision Research, Department of Ophthalmology, University of… Read More »Re-purposed drugs for retinitis pigmentosa may address mutation-independent approach for retinal degenerations.

Researchers based at the Nuffield Department of Clinical Neurosciences, The John Radcliffe Hospital, University of Oxford, have reported a new study on the mechanism of… Read More »AAV treatment or surgical issues on chorioretinal atrophy? Researchers report on a study on potential adverse events in a gene therapy treatment.

Researchers based at the Department of Biomedical Engineering, University of Houston, Texas and the Department of Ophthalmology, Duke University Medical Centre, Durham, North Carolina, have… Read More »Maintaining proper RHO:PRPH2 ratios in photoreceptors may provide a potential therapeutic approach for intervention.

A consortium of researchers across Australia, New Zealand, USA, Italy, Portugal, Singapore, Netherlands, Taiwan and Canada, have reported a new study evaluating clinical, electrophysiological and… Read More »Variants in peripherin 2 (PRPH2 gene) shows genetic, functional and clinical observations on 241 IRD patients. 

Researchers at the RIKEN BioResource Research Center, Kyoto, Japan, have reported that retinal organoids, derived from patients’ induced pluripotent stem cells (iPSCs) with a EYS… Read More »Retinal dystrophy caused by EYS dysfunction in retinal organoids shows significant phototoxicity from RIKEN research. 

Researchers at the Department of Ophthalmology, University of Turin, Italy, have reported a significant association between OCT biomarker measurements and reading performance in patients with… Read More »Association of retinal OCT biomarkers with reading performance in patients with diabetic macular edema (DME). 

Researchers at the Moorfields Eye Hospital and UCL Institute of Ophthalmology, University College London, UK, have reported the natural history of a retinopathy associated with… Read More »Natural history and characteristics of IQCB1(NPHP5) retinopathy may aim to measure relevant subsequent research outcomes.