Researchers at Radboud University Medical Center, Nijmegen, the Netherlands, have reported a novel approach to use exon skipping that may “patch” part of a gene… Read More »Therapeutic exon skipping strategies of Usher syndrome (USH2A) may provide mutation-independent approaches for treatment.
Researchers at the Institute of Basic Medical Sciences, University of Oslo, the Norwegian Association of the Blind and Partially Sighted, Oslo, and Roche Norway (F Hoffmann-La… Read More »Analysis reports the treatment burden of intravitreal anti-VEGF injections among a Norwegian cohort of patients and caregivers on nAMD.
Researchers at ProQR Therapeutics, an RNA company based in Leiden, the Netherlands, and with researchers at Radboud University Medical Center in Nijmegen, have reported results… Read More »Antisense oligonucleotide (AON) therapy for Stargardt disease type 1 (STGD1) provides a proof of concept with effective restoration of correct ABCA4 transcript splicing.
Researchers at the Shiley Eye Institute, University of California, San Diego, has reported results of AI (artificial intelligence) methods providing significantly accurate outcomes over manual… Read More »AI (artificial intelligence) study on multimodal images of RP patients shows significant impacts from both structural and functional evaluations.
Researchers at the Telethon Institute of Genetics and Medicine (TIGEM), Pozzuoli, Italy, has reported the results of 5,054 gene transcripts analysed from 218 IRD (inherited… Read More »A novel overview of the human retinal transcriptome may contribute missing heritability in IRD patients
Researchers at McMaster University, Hamilton, Ontario reported that a systematic review and meta-analysis of global prevalence of diabetic retinopathy (DR), in paediatric type 2 diabetes… Read More »Global priority that needs increased attention of diabetic retinopathy in children with Type 2 diabetes
Researchers at the Institute of Mathematics, Kassel University and the Department of Ophthalmology, Heidelberg University, have reported a novel in silico model and algorithm for… Read More »A novel in silico model and algorithm for refining therapeutic treatment of retinal disease
Researchers at the Department of Ophthalmology, Medical University Graz, Austria and the Department of Ophthalmology, University of Basel, Switzerland, have reported that fundus auto-fluorescence (FAF)… Read More »Fundus autofluorescence assessment tracks Stargardt disease progression for a 24-month period.
Researchers at the Seoul National University College of Medicine, Republic of Korea, have demonstrated a proof-of-principle using “base editing” (BEs) to address Leber congenital amaurosis… Read More »Visual function restoration for a pre-clinical in vivo IRD model using a novel therapeutic “base editing”.
A systematic review on the epidemiology of RPE65 mutations reported in the literature showed that there were significant variations of RPE65 proportions within countries as… Read More »A systematic literature review on the epidemiology of RPE65 mutations report significant variations in the literature within countries as well as regions.
