Researchers based in Queen’s University Belfast (QUB), UK have reported a systematic review of differential methylation in rare ophthalmic diseases. Methylation of key epigenomic biomarkers,… Read More »A research study of methylation as an epigenomic biomarker in rare ophthalmic diseases
Research at the Radboud University Medical Centre in Nijmegen, the Netherlands, has reported a phenotypic discordance between siblings with STGD1 having the same ABCA4 variants. … Read More »A research study of Stargardt disease (STGD1) highlights inter-sibling variability between genotype-phenotype
Research on a nation-wide study conducted in Israel has collated the largest cohort of inherited retinal disease (IRDs) to date. The Israel inherited retinal disease… Read More »A nation-wide study of inherited retinal disease reports the largest IRD cohort published in Israel
An editorial article published in Ophthalmology (AAO) outlines a useful guide for the deciphering of studies in artificial intelligence (AI)(2019 Nov;126(11):1475-1479). In an AAO opinion… Read More »An AAO editorial article in the journal Ophthalmology provides a field guide to harness artificial intelligence
Researchers at the Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, have reported that systematic reviews for retinal and vitreous conditions were… Read More »Research on research: systematic reviews for retinal and vitreous conditions are classified as not reliable
Researchers at the Joslin Diabetes Centre, Boston have identified that a protein can protect against diabetic retinopathy (DR) and potentially reverse the effects of complications… Read More »Research has shown that increased levels of retinol binding protein 3 (RBP3) may protect and treat diabetic retinopathy
Researchers at Radboud University Medical Center, Nijmegen, the Netherlands, have reported that phenotypic divergence between siblings with Stargardt disease (STGD1) carrying the same ABCA4 gene… Read More »Genotype-phenotype correlations in Stargardt disease highlight considerable complexity
Researchers at the Wilmer Eye Institute, Johns Hopkins University, Baltimore and the Boston University Schools of Medicine and Public Health, have provided a review paper… Read More »A systems biology approach aims to build new research activities on non-neovascular age-related macular degeneration.
Researchers at the National Eye Institute, Bethesda, MD, have demonstrated that C3 and CR3 proteins – components of the human innate immune system – have… Read More »US National Eye Institute suggests that the innate immune system may be a double-edged sword depending on the context of RP and AMD
The UK National Institute for Health Research (NIHR) has reported a high participation of the UK’s hospitals in clinical research ophthalmic studies. The study reports… Read More »UK’s National Institute for Health Research (NIHR) has reported on the composition and performance of ophthalmology research studies over 8-year period