Researchers at the Department of Ophthalmology, University of California, Irvine and the Structural Biology Research Centre, Vrije Universiteit Brussels, Belgium, have reported the use of… Read More »US & Belgium research team discover a novel “nanobody” (a “mini-antibody”) potentially applicable to retinitis pigmentosa (RP) treatment.
Researchers at the Institute of Ophthalmology, University College London and Moorfields Eye Hospital have reported that biomarkers, analysed by OCT scans, have shown reduced thickness… Read More »UCL Institute of Ophthalmology and Moorfields Eye Hospital publish data on OCT scan assessing biomarkers for neurodegeneration.
Research conducted at Sorbonne Université, INSERM, CNRS, Institut de la Vision, Paris, has reported three approaches to test novel strategies to treat a range of… Read More »Research for testing end-stage therapies for retinal degenerations for non-human primate (NHP) models.
Researchers at the University of Alabama, Birmingham, USA and Queensland University of Technology, Brisbane, Australia, have reported a study on the most highly cited articles… Read More »A first global analysis on ophthalmic journals and authors measuring the h-index – metrics for measuring scientific performance.
Researchers at the UCL Institute of Ophthalmology, London, UK have reported early pre-clinical research using non-viral gene therapy treatments for certain inherited retinal degenerations (IRDs),… Read More »Non-viral vectors for gene therapy may accommodate large genes, such as USH2A for Usher syndrome patients.
Researchers at Radboud University Medical Center, Nijmegen, the Netherlands, have reported a novel approach to use exon skipping that may “patch” part of a gene… Read More »Therapeutic exon skipping strategies of Usher syndrome (USH2A) may provide mutation-independent approaches for treatment.
Researchers at the Institute of Basic Medical Sciences, University of Oslo, the Norwegian Association of the Blind and Partially Sighted, Oslo, and Roche Norway (F Hoffmann-La… Read More »Analysis reports the treatment burden of intravitreal anti-VEGF injections among a Norwegian cohort of patients and caregivers on nAMD.
Researchers at ProQR Therapeutics, an RNA company based in Leiden, the Netherlands, and with researchers at Radboud University Medical Center in Nijmegen, have reported results… Read More »Antisense oligonucleotide (AON) therapy for Stargardt disease type 1 (STGD1) provides a proof of concept with effective restoration of correct ABCA4 transcript splicing.
Researchers at the Shiley Eye Institute, University of California, San Diego, has reported results of AI (artificial intelligence) methods providing significantly accurate outcomes over manual… Read More »AI (artificial intelligence) study on multimodal images of RP patients shows significant impacts from both structural and functional evaluations.
Researchers at the Telethon Institute of Genetics and Medicine (TIGEM), Pozzuoli, Italy, has reported the results of 5,054 gene transcripts analysed from 218 IRD (inherited… Read More »A novel overview of the human retinal transcriptome may contribute missing heritability in IRD patients