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Clinical

A review of fundus autofluorescence (FAF) underscores an indispensable technology for the diagnosis, monitoring and outcome measures of numerous retinal diseases.

Researchers at the Department of Ophthalmology, Vagelos College of Physicians and Surgeons, Columbia University, New York, have published a study outlining how fundus autofluorescence (FAF)… Read More »A review of fundus autofluorescence (FAF) underscores an indispensable technology for the diagnosis, monitoring and outcome measures of numerous retinal diseases.

Clinical study of >3,500 IRD patients reports novel genotype-phenotype associations using optical coherence tomography (OCT) imaging.  

Clinical researchers at the Institute of Ophthalmology, University College London, UK, and Moorfields Eye Hospital NHS Foundation Trust, London, have presented a novel deep learning… Read More »Clinical study of >3,500 IRD patients reports novel genotype-phenotype associations using optical coherence tomography (OCT) imaging.  

First quantitative choroidal assessment may be valuable for using other standard metrics for retinal clinical trial evaluations.

Researchers in Canada, have reported the first quantitative choroidal assessment in a cohort of patients with genetically characterized retinitis pigmentosa (RP). The results of the… Read More »First quantitative choroidal assessment may be valuable for using other standard metrics for retinal clinical trial evaluations.

Phase 3 trial of vorolanib intravitreal insert, using a tyrosine kinase inhibitor (TKI), will be evaluating for wet age-related macular degeneration (wet AMD).   

A Phase 3 randomised clinical trial has recruited of >400 patients in a seven-month period, driven by clinical and patient interest, according to the trial’s… Read More »Phase 3 trial of vorolanib intravitreal insert, using a tyrosine kinase inhibitor (TKI), will be evaluating for wet age-related macular degeneration (wet AMD).   

Clinical research on patients with infantile nystagmus syndrome (INS), across several inherited ocular diseases, may provide significant support for counselling and on-going clinical trials.   

Clinical researchers at the Department of Ophthalmology and the Vision Centre of Excellence, Akron Children’s Hospital, Ohio, have reported a molecular diagnostic rate of 41.5%… Read More »Clinical research on patients with infantile nystagmus syndrome (INS), across several inherited ocular diseases, may provide significant support for counselling and on-going clinical trials.   

Natural history of PCARE-associated retinopathy highlights genetics, clinical characteristics and time-to-event curves for development of atrophy. 

Clinical researchers at the Sorbonne Université, INSERM, CNRS, Institut de la Vision and  the Centre Hospitalier National d’Ophtalmologie des Quinze-Vingts, Paris, have reported PCARE-associated retinopathy… Read More »Natural history of PCARE-associated retinopathy highlights genetics, clinical characteristics and time-to-event curves for development of atrophy. 

New “CONSORT 2025 statement” has announced an expanded checklist to optimally conduct high-quality research on randomised trials. 

A consortium of clinical researchers and trial experts have launched a new updated statement published by 39 researchers*, led by Professor Sally Hopewell, based in… Read More »New “CONSORT 2025 statement” has announced an expanded checklist to optimally conduct high-quality research on randomised trials. 

Clinical analysis of phenotypic and genotypic characteristics on retinitis pigmentosa-1-like-1 (RP1L1) show associated retinopathy. 

Clinical researchers at the Sorbonne Université, INSERM, Institut de la Vision, Paris, have reported multiple pathogenic variants in the RP1L1 gene, associated with autosomal dominant,… Read More »Clinical analysis of phenotypic and genotypic characteristics on retinitis pigmentosa-1-like-1 (RP1L1) show associated retinopathy.