Research Articles

Repopulation of microglia cells in the retina may hold therapeutic promise in controlling inflammation and progression of RP and AMD

Researchers, based at the Unit on Neuron-Glia Interactions in Retinal Disease, National Eye Institute in Bethesda, MD, have shown that microglia in the retina of animal models can undergo repopulation leading to a renewal of organization and function. The discovery may have relevance for the development of therapeutic strategies to control inflammation and slow the […]

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Best’s disease gene therapy on horizon following successfully gene therapy rescue in canine models of human disease

Researchers, based at the School of Veterinary Medicine, University of Pennsylvania, and at the Scheie Eye Institute, also at Philadelphia’s University of Pennsylvania, have successfully treated animal models of the rare RPE disorder, Best’s disease, with a novel gene therapy. The macular degenerative disorder, caused by mutations in the Best1 gene, is generally detected in […]

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Gold-titanium nanowires show potential for restoring visual function in animal models of blindness

Researchers based at the Laboratory of Advanced Materials, located at the Department of Ophthalmology, Fudan University, Shanghai, have reported the restoration of visual function in animal models of retinal degeneration using gold plated titanium oxide nanowires. The Au-TiO2 nanowire array, developed by the Chinese research team, was shown to absorb light in the visible range […]

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