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Swiss research team demonstrates changes of the intestinal mircobiome may be associated with age-related macular degeneration (AMD)

A research project conducted at the University of Bern, led by Dr. Martin S. Zinkernagel, Dr. Denise C. Zysset-Burri and Prof. Dr. Dr. Sebastian Wolf, has demonstrated that the composition of the intestinal microbiome in patients with AMD, compared to controls, indicates an enrichment of certain microbial genera. The finding may open a significant field […]

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Regulators highlight that the development of new and clinically relevant biomarkers are key steps in accelerating the evaluation of novel ocular therapies.

An opinion paper authored by experts at the Medical Products Agency Uppsala, Sweden, and the European Medicines Agency, London, UK, has highlighted the need for new biomarker development to assist in accelerating the development of new treatments for a range of ocular disorders. The agencies comment that there are a significant number of ophthalmic indications […]

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Pre-clinical research shows re-programming of sugar metabolism may benefit electrophysiology and retinal anatomy in retinitis pigmentosa (RP) models.

Scientists based at the Department of Ophthalmology, Columbia University, New York, have shown that manipulating a metabolic pathway in photoreceptor cells may provide benefit in models of retinitis pigmentosa (RP). While the research is at a significantly early stage, the under-lying principle of re-programming sugar metabolism may provide a potential strategy to impact the course […]

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