Research Articles

Diabetic retinopathy screening study shows that financial incentives may have a negative effect on attendance at clinical appointments

Research conducted at Imperial College London has found that financial incentives designed to encourage patients to attend diabetic eye screening result in fewer attendees, compared to no incentive at all.  The randomised study demonstrated that participants receiving any incentive were actually less likely to attend for appointment compared to participants receiving no incentive.  The researchers […]

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Large European sample of autosomal dominant retinitis pigmentosa (adRP) families reveal landscape of genetic mutations behind pathology

Researchers, based at the Department of Genetics, Instituto de Investigación Sanitaria–Fundación Jiménez Díaz University Hospital–Universidad Autónoma in Madrid, have published research on the spectrum of mutations and genes involved in autosomal dominant retinitis pigmentosa (adRP). The research was carried out on 258 unrelated Spanish families with a clinical diagnosis of RP and suspected autosomal dominant […]

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Researchers show how proteasome modification may provide a therapeutic strategy to dealing with dominant-negative retinitis pigmentosa (RP).

Researchers, based at the Department of Ophthalmology, Duke University School of Medicine, have shown how modification of the proteasome in photoreceptor cells may be used to enhance the disposal of mis-folded or mis-targeted protein. Ridding retinal cells of such dysfunctional protetins has the potential to bring about therapeutic benefit to patients suffering ocular disorders such […]

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