A report published in Nature Medicine has shown that an RNA antisense oligonucleotide (AON) treatment, directed to the CEP290 gene for LCA10, found one patient… Read More »Leber congenital amaurosis (LCA) reports a sustained improvement for the treatment of a novel anti-oligonucleotide (AON) therapy.
The EMA’s Pharmacovigilance Risk Assessment Committee (PRAC) has reported that safety-related aspects of Eylea (aflibercept) may lead to “a higher-than-expected proportion of cases of increased… Read More »The EMA has advised that pre-filled syringes with aflibercept can lead to IOP issues if not correctly handled.
Researchers at the Institute of Genetics, TCD, Dublin and the Department of Ophthalmology, McGill University, Montreal have reported significant research results supporting replenishment of the… Read More »Therapeutic implications reported in relation to a unique dominant RPE65 mutation with autosomal dominant retinitis pigmentosa (adRP)
A systematic review, published in the European Journal of Ophthalmology, has reported a significant number of peer-reviewed studies on ophthalmic-focused COVID-19 articles. A study conducted… Read More »A systematic review has reported ophthalmology-focused publications and findings on COVID-19 pandemic.
Research on road driving testing with participants with ocular diseases, compared to aged-matched controls, has shown a significant time delay on a useful hazard perception… Read More »Research on hazard perception testing (HPT) among older drivers with eye disease can be improved with training.
An estimate of 100,000 ophthalmic appointments have been cancelled by a single hospital (Moorfields, London, UK) over a 3-month duration due to the COVID-19 pandemic. … Read More »Stay-at-home visual evaluations provide an innovative tool for printable visual acuity (VA) charts
An international consortium of over 80 of the world’s experts in low vision (LV) and ultra low-vision (ULV) in the field of vision restoration has… Read More »Low vision (LV) and ultra low-vision (ULV) assays address several key recommendations on the measurement and reporting of patient outcomes in vision restoration trials
Researchers based at the University of Cambridge, UK, have reported intriguing results from a Phase 3 trial for a gene therapy treatment of Leber hereditary… Read More »A “failed” clinical trial study showed improved treatment in LHON patients with results in both study and control eyes
A team of clinical researchers based at Johns Hopkins Hospital, Baltimore, Maryland, has reported findings of equivalent efficacy and similar safety and immunogenicity profiles with… Read More »A phase 3 study for a biosimilar of ranibizumab for neovascular AMD has reported equivalent efficacy and similar safety for 705 nAMD patients.
Clinical researchers at the NHS Foundation Trust, Sheffield, UK have found that real-world evidence on the effectiveness and safety of a fluocinolone acetonide (FAc) implant… Read More »Real-world data on fluocinolone acetonide implant treatment with recurrent diabetic macular oedema (DMO) supports fewerclinical visits over 3 years.