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Clinical Articles

Pentosan polysulfate sodium (PPS), a treatment for interstitial cystitis, has raised concerns for a contraindication of macular disease on long term effects.

A clinical research report in the British Journal of Ophthalmology has indicated that the use of pentosan polysulfate sodium (PPS, registered as “Elmiron”, Janssen Pharmaceuticals) is now associated with a new diagnosis of macular disease at a seven-year follow-up in a large retrospective matched cohort study.  PPR / Elmiron is marketed for the treatment of […]

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A systematic review and meta-analyses shows the prevalent and incidence of age-related macular degeneration in Europe

A systematic review and meta-analysis on age-related macular degeneration in Europe has reported an increasing prevalent and incident data until 2050. The analysis of the research indicates that there will be considerable healthcare supports required over the European healthcare systems over the coming decade. The research, funded by the European Society of Retina Specialists (EURETINA) […]

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A systematic review with meta-analyses showed peripheral retinal lesions in eyes with AMD using ultra-widefield imaging

Researchers at the Department of Ophthalmology, Zealand University Hospital, Denmark, showed that peripheral changes in UWFI (ultra-widefield imaging) were found to be highly prevalent in eyes with AMD.  The systematic review and meta-analysis supported the claim that AMD disease is pan-retinal and not macula only. The researchers indicated that clinical significance of peripheral lesions in AMD […]

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