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Clinical Articles

A systematic review with meta-analyses showed peripheral retinal lesions in eyes with AMD using ultra-widefield imaging

Researchers at the Department of Ophthalmology, Zealand University Hospital, Denmark, showed that peripheral changes in UWFI (ultra-widefield imaging) were found to be highly prevalent in eyes with AMD.  The systematic review and meta-analysis supported the claim that AMD disease is pan-retinal and not macula only. The researchers indicated that clinical significance of peripheral lesions in AMD […]

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Phase II study results on intravitreal (IVT) pegcetacoplan (a synthetic cyclic peptide) for the treatment of geographic atrophy (GA) secondary to ARMD

A Phase II study investigating intravitreal pegcetacoplan for the treatment of geographic atrophy (GA), secondary to age-related macular degeneration (AMD), has announced the reporting of statistically significant reductions in the growth of GA, compared with sham treatment.  Results, published in the journal Ophthalmology (article in press, 2019), showed the GA growth rate was reduced by […]

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Two different treat-and-extend protocols with aflibercept in wet AMD suggest fewer injections

Researchers at the Helsinki Retina Research Group at the University of Helsinki, Finland report that while two treatment protocols – either moderate or rapid extensions – do not change the visual acuity or central subfield macular thickness (CSMT), the mean number of injections was lower and the treatment interval longer in the treat-and-extend group with […]

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