A clinical research team based at the Yale University School of Medicine have reported that best-corrected visual acuity (BVCA) in eyes with choroideremia (CHM) appears… Read More »A visual acuity study on long-term natural history of choroideremia research suggests that BCVA has a 2-phase model
Clinical researchers at the University College London, with Moorfields Eye Hospital and Guy’s and St. Thomas’, have reported a valuable correlation between anatomical measurement and… Read More »Clinical trial research for new endpoints propose ellipsoid measurement for both anatomical and visual outcomes.
Clinical researchers at the University Hospital Tuebingen has published a report on an AAV-CNGA3 gene therapy treatment among 9 patients. The results of the clinical… Read More »Clinical trial research for gene therapy for CNGA3-linked achromatopsia has reported on safety and vision outcomes.
A clinical research study published in The Lancet has reported that the treatment of eplerenone should be discontinued for the use of serous chorioretinopathy (CSCR)… Read More »A clinical research study using eplerenone for central serous chorioretinopathy (CSCR) recommends that ophthalmologists should stop the use of the treatment.
Multiple clinical trials are now in progress aimed at developing COVID19 vaccines, repurposing drugs or new treatments running across the US, Canada, Europe and China. … Read More »A promising treatment – Remdesivir – is now progressing a clinical trial for COVID19 supported by the National Institutes of Health
Research from the University of Oxford has reported early results from the first-in-human Phase 1/2, dose-escalation clinical trial for X-linked RP caused by mutations in… Read More »Early clinical results report gene therapy treatment for X-linked retinitis pigmentosa caused by mutations in RPGR
Research from a retrospective analysis of 10 randomized clinical trials reporting on 390 subjects in investigator-initiated trials found 178 participants (45.6%) were noncompliant, while 212… Read More »Non-compliance in clinical trials of retinal studies report a significant loss-to-follow up on patient numbers
Research at the Centre for Public Health, Queen’s University Belfast, UK, has suggested that a core outcome set (COS) of measurements should be used in… Read More »Clinical trial outcomes for geographic atrophy provides valuable data from both patient and expert input
Clinical research has indicated that almost half of trial studies have noncompliance issues, creating negative impact outcomes for research. A recent study has shown that… Read More »Retinal clinical trials indicate that almost 50% of studies have non-compliance issues
A brief clinical update reporting on a new anti-VEGF antibody conjugate polymer (identified as KSI-301) has highlighted visual acuity gains with three indications – wet… Read More »Phase 1b study of a new anti-VEFG antibody has reported BCVA gains across wet AMD, diabetic macular edema and retinal vein occlusion