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Market/Novel Tech

GenSight, a French biotechnology company, has announced the receipt of FDA orphan designation for retinitis pigmentosa gene therapy treatment in the US.

GenSight Biologics S.A. (Euronext: SIGHT) has announced the receipt of FDA Orphan Drug Designation in the US for its experimental retinitis pigmentosa (RP) treatment, “GS030”. The announcement follows a similar orhan designation grant in the EU, announced in Q4 of 2016. According to the company, GS030, is an optogenetic therapy delivered using adeno-associated viral (AAV) […]

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Phase IIa trial recruits first patient for novel therapy directed towards treatment of Stargardt’s disease.

A Phase IIa human study, sponsored by Acucela Inc., based in Seattle, Washington, has announced the recruitment of its first patient to evaluate emixustat hydrochloride in subjects with macular atrophy secondary to Stargardt disease. The experimental small molecule treatment, a visual cycle modulator, will be tested in a multicenter, randomized, blinded study to investigate the […]

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Research

Potential biomarker for diabetic retinopathy uncovered through genome-wide mRNA analysis

Researchers based at the Institute of Ophthalmology, Conde de Valenciana, Mexico City, have published the results of a genome wide mRNA screen which suggest a potential link between alternative splice forms of the TUBD1 gene, and a risk for developing diabetic retinopathy (DR). While the study was performed on a relatively small number of diabetic […]

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Introduction

February 18th, 2017: “EURETINA-Brief”© Issue No. 148

by Dr. Gearóid Tuohy   Dear EURETINA Members,   A very warm welcome to the February 18th, 2017 edition of EURETINA’s web-based digital magazine, “EURETINA Brief”. EURETINA are delighted to continue our delivery of up-to-date summary briefs on a range of topics of interest to retinal clinicians, specialists and researchers across Europe. This resource is […]

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January 3rd, 2017: “EURETINA-Brief”© Issue No. 146

by Dr. Gearóid Tuohy   Dear EURETINA Members,   A very warm welcome to the January 3rd, 2017 edition of EURETINA’s web-based digital magazine, “EURETINA Brief”. EURETINA are delighted to continue our delivery of up-to-date summary briefs on a range of topics of interest to retinal clinicians, specialists and researchers across Europe. This resource is […]

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Findings from an international genomics consortium almost double the number of associated genetic loci and variants for AMD

Research conducted by the International AMD Genomics Consortium (IAMDGC) has recently reported an almost doubling in the number of genetic risk loci associated with age-related macular degeneration (AMD). In a significant publication in the journal Nature Genetics, the research group has reported on an analysis of >12 million gene variants, “including 163,714 directly genotyped, mostly […]

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