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Market/Novel Tech

Applied Genetic Technologies Corporation (Nasdaq: AGTC) reports interim Phase 1/2 achromatopsia study data

Applied Genetic Technologies Corporation (Nasdaq: AGTC), a gene therapy company in Florida, has reported encouraging interim six-month data from dose-escalation cohorts of a Phase 1/2 trial in patients with achromatopsia.  According to the sponsor, interim results demonstrated “encouraging signs of biologic activity and a favorable safety profile”.  The study is listed at the US clinical […]

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Clinical trial outcomes for geographic atrophy provides valuable data from both patient and expert input

Research at the Centre for Public Health, Queen’s University Belfast, UK, has suggested that a core outcome set (COS) of measurements should be used in geographic atrophy (GA) trials.  The core outcome set of measurements are proposed to include patient-reported outcome measures, near visual acuity, reading speed and assessment of the outer retina.  According to […]

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Research

Non-responders of anti-VEFG treatments for AMD identify certain genetic variants in the VEGF pathway

Researchers at the Department of Ophthalmology at Ghent University Hospital have reported that the identification of genetic variants from wet AMD patients do not provide benefit for anti-VEFG treatments (ranibizumab and bevacizumab).  The researchers identified several SNPs (single nucleotide polymorphisms) associated with anti-VEFG treatments that did not respond to drug therapy, particularly three genes – […]

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Introduction

February 11th, 2020: “EURETINA-Brief”© Issue No. 207

by Dr. Gearóid Tuohy     Dear EURETINA Members,   A very warm welcome to the February 11th, 2020 edition of EURETINA’s web-based digital magazine, “EURETINA Brief”.  EURETINA are delighted to continue our delivery of up-to-date summary briefs on a range of topics of interest to retinal clinicians, specialists and researchers across Europe. This resource […]

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Introduction

December 18th, 2019: “EURETINA-Brief”© Issue No. 204

by Dr. Gearóid Tuohy   Dear EURETINA Members,   A very warm welcome to the December 18th, 2019 edition of EURETINA’s web-based digital magazine, “EURETINA Brief”.  EURETINA are delighted to continue our delivery of up-to-date summary briefs on a range of topics of interest to retinal clinicians, specialists and researchers across Europe. This resource is […]

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Genetics and Genomics of Eye Disease, 1st Edition – Advancing to Precision Medicine (Elsevier) Editors: Xiaoyi Gao Ph.D.

Genetics and Genomics of Eye Disease, 1st Edition – Advancing to Precision Medicine (Elsevier) Editors: Xiaoyi Gao Paperback ISBN: 9780128162224 eBook ISBN: 9780128167274; Pages 383, Academic Press, Published Date: 13th September 2019   Medicine has made enormous strides in the 33 years since Tom Roderick, Victor McKusick and Frank Ruddle coined the term “genomics”, outlined […]

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