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Dutch company ProQR announces the receipt of FDA authorisation to initiate Phase I/II study for Leber congenital amaurosis, type 10 (LCA10)

Dutch biotechnology company ProQR Therapeutcis N.V., (NASDAQ:PRQR), Leiden, The Netherlands, has announced the receipt of “fast-track” designation from the FDA for their clinical stage development of “QR-110”, an experimental gene editing treatment for Leber’s congenital amaurosis (LCA), type 10. Fast track designation is granted by the FDA to sponsors of treaments under development for serious […]

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UK multicentre real-world study demonstrates a sharp increase in diabetic macular oedema following cataract surgery

Research conducted on behalf of the UK Diabetic Retinopathy Electronic Medical Record (UK DR EMR) Users Group has shown that the rate of developing “treatment-requiring” diabetic macular oedema (DMO), following cataract surgery, increases dramatically, peaking in the 3-6 months’ postoperative period. In addition, the research demonstrated that patients with moderate and severe non-proliferative diabetic retinopathy (NPDR) […]

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Research

Swiss research team demonstrates changes of the intestinal mircobiome may be associated with age-related macular degeneration (AMD)

A research project conducted at the University of Bern, led by Dr. Martin S. Zinkernagel, Dr. Denise C. Zysset-Burri and Prof. Dr. Dr. Sebastian Wolf, has demonstrated that the composition of the intestinal microbiome in patients with AMD, compared to controls, indicates an enrichment of certain microbial genera. The finding may open a significant field […]

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Introduction

June 13th, 2017: “EURETINA-Brief”© Issue No. 155

by Dr. Gearóid Tuohy   Dear EURETINA Members,   A very warm welcome to the June 13th, 2017 edition of EURETINA’s web-based digital magazine, “EURETINA Brief”. EURETINA are delighted to continue our delivery of up-to-date summary briefs on a range of topics of interest to retinal clinicians, specialists and researchers across Europe. This resource is […]

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Findings from an international genomics consortium almost double the number of associated genetic loci and variants for AMD

Research conducted by the International AMD Genomics Consortium (IAMDGC) has recently reported an almost doubling in the number of genetic risk loci associated with age-related macular degeneration (AMD). In a significant publication in the journal Nature Genetics, the research group has reported on an analysis of >12 million gene variants, “including 163,714 directly genotyped, mostly […]

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Findings from an international genomics consortium almost double the number of associated genetic loci and variants for AMD

Research conducted by the International AMD Genomics Consortium (IAMDGC) has recently reported an almost doubling in the number of genetic risk loci associated with age-related macular degeneration (AMD). In a significant publication in the journal Nature Genetics, the research group has reported on an analysis of >12 million gene variants, “including 163,714 directly genotyped, mostly […]

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