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Converting rods into cones in a model of retinitis pigmentosa (RP) rescues retinal degeneration.

Inherited retinal disorders (IRDs) are estimated to affect millions of individuals on a global scale, in many instances leading to significantly reduced vision or blindness. The term “IRD” acts as an umbrella label for many different types of ocular disease and, on a genetic level, it is estimated that almost 200 distinct genes are the […]

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Market/Novel Tech

Shire Pharmaceuticals acquires Foresight Biotherapeutics Inc. to gain infectious conjunctivitis treatment entering Phase III

Shire plc (LSE: SHP, NASDAQ: SHPG) has announced the acquisition of Foresight Biotechnologies Inc., based in New York for $300 million in an all-cash deal. According to the companies, the transaction provides Shire with the exclusive global rights to a topical ophthalmic solution, “FST-100”, developed for the treatment of late-stage infectious conjunctivitis and a potential […]

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Safety and efficacy of ocular iontophoresis with dexamethasone solution undergoes clinical testing with novel delivery system

A Phase Ib/IIa clinical trial has reportedly treated the first macular edema patient with a novel delivery system designed to increase compliance and improve drug delivery to the posterior segment. The novel iontophoresis device is loaded with a specific formulation of dexamethasone phosphate and is placed on the patient’s eye following which electrical current facilitates […]

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Genetic risk score on select genes provides predictive tool for second eye involvement in AMD

Research, led by scientists at the Kyoto University Graduate School of Medicine, Japan, has demonstrated that the Genetic Risk Score (GRS), using five previously characterised risk genes, ARMS2, CFH, TNFRSF10A, VEGFA and CFI, show a significant association with second-eye involvement in AMD. While a number of genome wide association studies of AMD in the first […]

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August 18th, 2015: “EURETINA-Brief”© Issue No. 115

by Dr. Gearóid Tuohy   Dear EURETINA Members,   A very warm welcome to the August 18th, 2015 edition of EURETINA’s web-based digital magazine, “EURETINA Brief”. EURETINA are delighted to continue our delivery of up to date summary briefs on a range of topics of interest to retinal specialists and researchers across Europe. This resource […]

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