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Expert research scientists in demand to support evaluation of new drug approvals for novel technologies, including retinal stem cell and gene therapies

The pace of new technology and novel medical treatments has reached a point at which regulators and assessors require additional expert evaluation in reviewing and assessing marketing authorizations. A recent Nature editorial has called for increased support from research scientists into translational medicine, specifically in regards to cutting edge and novel technologies now seeking marketing […]

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Market/Novel Tech

Topline data from GenSight’s Phase III REVERSE study provide an unusual and unexpected outcome

  GenSight Biologics S.A. (Euronext: SIGHT) has announced topline results from the company’s Phase III “REVERSE” clinical study of an experimental gene therapy, ”GS010”, designed for the treatment of Leber Hereditary Optic Neuropathy (LHON). According to the company, the study evaluated the safety and efficacy of a single intravitreal injection of GS010 (rAAV2/2-ND4) in 37 […]

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FDA approves first AI enabled software diagnostic to detect diabetic retinopathy without human graders

  The US FDA has announced the authorization of an AI (artificial intelligence) enabled software diagnostic for the screening of diabetic patients for retinopathy. The approved device, manufactured by US company IDx, uses specialized software to determine the status of a fundus image and adjudicate whether or not specialist ophthalmic consultancy is required. As the […]

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Repopulation of microglia cells in the retina may hold therapeutic promise in controlling inflammation and progression of RP and AMD

Researchers, based at the Unit on Neuron-Glia Interactions in Retinal Disease, National Eye Institute in Bethesda, MD, have shown that microglia in the retina of animal models can undergo repopulation leading to a renewal of organization and function. The discovery may have relevance for the development of therapeutic strategies to control inflammation and slow the […]

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April 17th, 2018: “EURETINA-Brief”© Issue No. 174

by Dr. Gearóid Tuohy   Dear EURETINA Members,   A very warm welcome to the April 17th, 2018 edition of EURETINA’s web-based digital magazine, “EURETINA Brief”. EURETINA are delighted to continue our delivery of up-to-date summary briefs on a range of topics of interest to retinal clinicians, specialists and researchers across Europe. This resource is […]

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Whole exome sequencing (WES) continues to yield significant efficiencies in clinical identification of inherited retinal degenerations.

Research results reported by investigators based at the Department of Genetics & Microbiology, University of Barcelona, Spain, have shown that whole exome sequencing (WES) continues to provide efficient returns in the identification of the genetic diagnosis for a range of inherited retinal disorders. The Spanish research group worked on a cohort of 33 families with […]

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