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Featured

Converting rods into cones in a model of retinitis pigmentosa (RP) rescues retinal degeneration

Inherited retinal disorders (IRDs) are estimated to affect millions of individuals on a global scale, in many instances leading to significantly reduced vision or blindness. The term “IRD” acts as an umbrella label for many different types of ocular disease and, on a genetic level, it is estimated that almost 200 distinct genes are the […]

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Market/Novel Tech

Shire plc sign research agreement with Foundation Fighting Blindness on development of treatments for autosomal dominant retinitis pigmentosa

Shire plc (LSE: SHP, NASDAQ: SHPG) and the US Foundation Fighting Blindness (FFB) are set to collaborate on a new initiative to accelerate the development of therapies that could treat autosomal dominant retinitis pigmentosa (adRP). The company has demonstrated a significant expansion of its business interests in the ophthalmic market in recent years, now under-scored […]

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Featured

UK expert panel publish recommendations on use of aflibercept after year 1

An expert panel of clinical ophthalmologists, assembled in London by Bayer HealthCare, has issued recommendations in relation to the administration of aflibercept (Eylea) in wet age-related macular degeneration (AMD) after year 1. The published findings coincide with an increasing number of patients completing their first year of treatment since the approval of aflibercept in the […]

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Research

University of Alberta launches first ocular gene-therapy clinical trial in Canada

Researchers at the University of Alberta, Canada have announced the initiation of enrolment and dosing in a Phase II clinical trial of a novel gene therapy for the treatment of choroideremia (CHM). The therapeutic approach will use a viral vector, adeno-associated virus (AAV), to deliver a wild-type copy of the Rab-escort protein 1 (REP-1) gene […]

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Introduction

July 17th, 2015: “EURETINA-Brief”© Issue No. 113

by Dr. Gearóid Tuohy   Dear EURETINA Members,   A very warm welcome to the July 17th, 2015 edition of EURETINA’s web-based digital magazine, “EURETINA Brief”. EURETINA are delighted to continue our delivery of up to date summary briefs on a range of topics of interest to retinal specialists and researchers across Europe. This resource […]

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Research

Increase in placental growth factor (PlGF) levels observed following aflibercept (Eylea) treatment.

Research, led by scientists at the Department of Ophthalmology, Medical University Innsbruck, Austria, has demonstrated a significant increase in systemic levels of placental growth factor (PlGF) following intravitreal aflibercept (Eylea) treatment. If representative across larger numbers of patients the finding may have implications for optimizing clinical outcomes in age related macular degeneration. Although the total […]

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