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Converting rods into cones in a model of retinitis pigmentosa (RP) rescues retinal degeneration

Inherited retinal disorders (IRDs) are estimated to affect millions of individuals on a global scale, in many instances leading to significantly reduced vision or blindness. The term “IRD” acts as an umbrella label for many different types of ocular disease and, on a genetic level, it is estimated that almost 200 distinct genes are the […]

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Market/Novel Tech

Ophthotech Corporation receives $50M milestone payment from Novartis for development of Fovista

Ophthotech Corporation (Nasdaq: OPHT) has announced that it has reached a second $50 million milestone payment from Novartis Pharma AG as part of an ex-US licensing and commercialization agreement for the company’s lead compound, Fovista. According to the company’s press release, Ophthotech has attained $300 million in upfront fees and milestone payments since May 2014, […]

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Biomarker involved in proliferative diabetic retinopathy (PDR) highlights potential role of M2 macrophage

Clinical research led by a Japanese team at Kyushu University Graduate School of Medical Sciences, Fukuoka, has suggested that overexpression of CD163 in the vitreous and fibrovascular membranes of patients with proliferative diabetic retinopathy (PDR) points to M2 macrophage involvement with progression of the disease. Levels of CD163 – a specific marker for M2 macrophage […]

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Sodium salicylate improves retinal function and reduces insulin resistance in retina of type 2 diabetic models

Research led by scientists at Wayne State University, Detroit, Michigan, has demonstrated that salicylate may improve retinal function by enhancing insulin signaling in the retina of type 2 diabetic animal models and in cultured retinal cells. The medicinal properties of salicyclate, an important active ingredient of aspirin, are known to have anti-inflammatory, antipyretic and analgesic […]

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April 17th, 2015: “EURETINA-Brief”© Issue No. 107

Dear EURETINA Members,   A very warm welcome to the April 17th, 2015 edition of EURETINA’s web-based digital magazine, “EURETINA Brief”. EURETINA are delighted to continue our delivery of up to date summary briefs on a range of topics of interest to retinal specialists and researchers across Europe. This resource is designed to accommodate the […]

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