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Market/Novel Tech

University of Oxford retinal gene therapy company, Nightstar Therapeutics Ltd., files application to float on US NASDAQ.

Nightstar Therapeutics Ltd., a retinal gene therapy company spun out of the University of Oxford, UK, has filed a Form-1 with the United States SEC to raise up to $86.25M in an initial public offering on the NASDAQ Global Market. The company will adopt the symbol “NITE”. In their registration statement to float the company, […]

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Systematic review of antioxidant vitamin and mineral use in preventing AMD suggests no benefit when analysed in >76,000 people

A systematic review and meta-analysis to determine whether or not taking antioxidant vitamin or mineral supplements, or both, prevent the development of AMD has found no evidence of benefit to their use. The study, conducted by researchers from the London School of Hygiene & Tropical Medicine and the City University of London, published their findings […]

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Research

Research published in Ophthalmologica shows aflibercept “treat and extend” (TAE) protocol is efficacious in typical AMD patients.

Research, reported in EURETINA’s professional journal, Ophthalmologica, has shown that a treat-and-extend (“TAE”) regimen using aflibercept for typical AMD appears effective for improving AMD and exudative changes. In addition the investigators commented that the exudation observed in participants may be suppressed with fewer treatments in classic choroidal neovascularisation (CNV), compared to occult CNV. The research, […]

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Introduction

September 16th, 2017: “EURETINA-Brief”© Issue No. 161

by Dr. Gearóid Tuohy   Dear EURETINA Members,   A very warm welcome to the September 16th, 2017 edition of EURETINA’s web-based digital magazine, “EURETINA Brief”. EURETINA are delighted to continue our delivery of up-to-date summary briefs on a range of topics of interest to retinal clinicians, specialists and researchers across Europe. This resource is […]

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Whole exome sequencing (WES) continues to yield significant efficiencies in clinical identification of inherited retinal degenerations.

Research results reported by investigators based at the Department of Genetics & Microbiology, University of Barcelona, Spain, have shown that whole exome sequencing (WES) continues to provide efficient returns in the identification of the genetic diagnosis for a range of inherited retinal disorders. The Spanish research group worked on a cohort of 33 families with […]

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Findings from an international genomics consortium almost double the number of associated genetic loci and variants for AMD

Research conducted by the International AMD Genomics Consortium (IAMDGC) has recently reported an almost doubling in the number of genetic risk loci associated with age-related macular degeneration (AMD). In a significant publication in the journal Nature Genetics, the research group has reported on an analysis of >12 million gene variants, “including 163,714 directly genotyped, mostly […]

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