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The effects of zinc on the prevention and treatment of AMD are far from conclusive, according to a systematic review

Research from Tufts University, Boston, has indicated that evidence remains inconclusive in regards to whether or not zinc intake from foods and supplements is beneficial in the primary prevention and treatment of AMD.   Analysis, published in the journal, Investigative Ophthalmology & Visual Science (Vishwanathan et al, Vol. 54, No. 6, pp 3985-3998) show that while […]

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Market/Novel Tech

RetroSense Therapeutics announces IND application for novel optogenetic RP therapy

RetroSense Therapeutics LLC, a private company based in Ann Arbor, Michigan, has announced receipt of clearance from the FDA to initiate a first-in-human study of an optogenetic strategy for the treatment of retinitis pigmentosa (RP). The company aims to deliver a “channelrhodopsin 2” gene, originally isolated from a green alga and transfect the gene into […]

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University of California review highlights increasing activity in clinical trial stem cell research

A review in the journal Expert Opinion on Biological Therapy (http://dx.doi.org/10.1517/14712598.2016.1093110) has highlighted the existence of almost 20 clinical trials, either completed or on-going, in the field of retinal degenerative stem cell treatment. The review points out that considerable progress made in the scientific field has directly led to a number of human studies on […]

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Mitochondrial DNA (mtDNA) provides novel mechanistic link to release of pro-inflammatory cytokines and AMD pathogenesis.

Research, led by scientists at the Massachusetts Eye and Ear Infirmary, Harvard Medical School, has shown a mechanistic link between fragments of mitochondrial DNA (mtDNA) and the secretion of pro-inflammatory cytokines from RPE cells. The increased activity of interleukin-6 (IL-6) and interleukin-8 (IL-8) in the presence of mtDNA fragments demonstrates a possible pathway in which […]

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October 2nd, 2015: “EURETINA-Brief”© Issue No. 118

  by Dr. Gearóid Tuohy   Dear EURETINA Members,   A very warm welcome to the October 2nd, 2015 edition of EURETINA’s web-based digital magazine, “EURETINA Brief”. EURETINA are delighted to continue our delivery of up to date summary briefs on a range of topics of interest to retinal specialists and researchers across Europe. This […]

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