A consortium of researchers, led by Iowa State University & the University of Louisville, have reported the successful generation of a new large animal model for use in the development of new therapies to treat retinal degenerative disease. The miniature-pig model, harbouring the Pro23His rhodopsin mutation, was created by somatic cell nuclear transfer (SCNT) and is described in detail in a publication in Investigative Ophthalmology & Visual Science (2012, 53, 1, 501-507). The model is expected to provide a significant research tool to the increasing numbers of translational research projects aiming to progress new therapies to the clinic.
New miniature pig model mimics the most common form of dominant retinitis pigmentosa in humans
- by swdadmin