Research conducted at the Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, has shown that CRISPR/Cas9 gene editing technology may be capable of correcting dominant… Read More »New CRISPR/Cas9 gene editing tool indicates a 35% visual acuity improvement in model of autosomal dominant retinitis pigmentosa
Research, conducted across 42 ophthalmology centres in the United States, has reported that point-of-care measurement of hemoglobin A1c (HbA1c), combined with personalized diabetes risk assessment… Read More »Research suggests that the impact of individualized patient assessment and diabetes-risk education on glycemic control may not be sufficiently effective
Research conducted by an international consortium of ophthalmic genetic specialists has reported the identification of a further three loci believed to contribute to the pathology… Read More »Genomic meta-analysis across patient DNA of European ancestry uncovers three additional genetic loci behind glaucoma
Research conducted by the International AMD Genomics Consortium (IAMDGC) has reported an almost doubling in the number of genetic risk loci associated with age-related macular… Read More »Findings from an international genomics consortium almost double the number of associated genetic loci and variants for AMD
Early stage research, conducted at the Department of Ophthalmology, Pennsylvania State University, has indicated that hydrogel discs loaded with insulin lispro and inserted sub-conjunctivally, may… Read More »Sustained insulin release in a model of diabetic retinopathy (DR) rescues retinal cells from apoptotic cell death
Collaborative research between research groups in the US and China has indicated a mechanistic link between high-risk genetic alleles found to be associated with primary… Read More »Death of retinal ganglion cells (RGCs) may be mediated by up-regulation of a kinase inhibitor in concert with genetic risk variants
A systematic review of interventions for diabetic retinopathy, published in the American Journal of Ophthalmology, has found that intensive insulin pump therapy, compared to multiple… Read More »Systematic review and meta-analyses indicates that intensive insulin therapy reduces incidence of diabetic retinopathy
A comprehensive 5-year prospective study across 72 centres in the US has shown that a significant level of antibiotic resistance exists among common ocular pathogens.… Read More »Nationwide study in the US indicates antibiotic resistance among ocular pathogens remains high.
Results from collaborative research between Isis Pharmaceuticals, the University of California at San Francisco and GlaxoSmithKlein UK, has shown that second generation anti-sense molecules targeting… Read More »Second generation anti-sense oligonucleotides show efficacy in dominant retinitis pigmentosa (RP) model.
Research, led by scientists at the Massachusetts Eye and Ear Infirmary, Harvard Medical School, has shown a mechanistic link between fragments of mitochondrial DNA (mtDNA)… Read More »Mitochondrial DNA (mtDNA) provides novel mechanistic link to release of pro-inflammatory cytokines and AMD pathogenesis.