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US study questions the importance of drusen in the conversion of dry AMD to neovascular AMD

Research conducted at the University of Pittsburg has suggested that drusen area, the presence of large drusen and the presence of hyperpigmentation were not consistent risk factors in the development of choroidal neovacularisation (CNV). Instead, the research showed that an affected fellow eye was the strongest and most consistent risk factor across all models. In addition, the study found that a large drusen area does not necessarily mean an increased risk of conversion from dry to wet AMD.