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New research suggests proinsulin administration may reduce vision loss in retinitis pigmentosa models

Novel research from the University of Alicante, Spain has suggested that the administration of proinsulin may be capable of slowing retinal degeneration and vision loss in a model of retinitis pigmentosa. The research study, led by Drs. Laura Fernandez-Sanchez and Nicolas Cuenca, reported that a single systemic injection appeared to reduce the level of visual deterioration and led to a significant preservation of photoreceptor cells compared to control tests. The authors of the work describe the study as the first proinsulin therapy in an animal model using a gene therapy approach.