A double blind Phase III trial in 691 patients has reported that 0.5mg Lucentis plus prompt or deferred laser therapy had a significant improvement in BCVA score compared to laser therapy alone (9 vs. 3 letters, p<0.001). The randomized trial, supported by Allergan and Genentech, compared ranibizumab plus prompt or deferred laser with triamcinoclone plus prompt laser for the treatment of diabetic macular edema (DME). As a result, Lucentis may become part of the standard of care for the treatment of DME and become incorporated into national treatment guidelines by the American Academy of Ophthalmology (AAO).
Lucentis (ranibizumab) plus laser treatment for DME raises bar for new therapies
- by swdadmin