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Japanese clinical study highlights role of inflammation in retinitis pigmentosa (RP).

Clinical research, conducted by a team from the Graduate School of Medical Sciences, Kyushu University, Japan, suggest that medical interventions for ocular inflammatory reactions may provide benefit for patients with retinitis pigmentosa (RP). The research, conducted on three hundred and seventy-one patients diagnosed with typical RP, included 165 patients without active inflammatory disease. Results from the study indicated that 37.3% of eyes analysed had signs of inflammatory cells in the anterior vitreous cavity with a stronger inflammatory reaction associating with younger age. In addition, the levels of pro-inflammatory cytokines and chemokines, appeared to be increased in the aqueous and vitreous of RP patients relative to the levels found in controls. The authors of the research conclude that the “results, supported by considerable evidence from other studies, suggest that intervention/suppressors of inflammation should be considered as a potential therapy in the treatment of RP”.